Podcast: a16z

Venture capital has powered companies like Facebook and TikTok—but what if that same urgency fueled America’s defense and industrial base? Katherine Boyle, General Partner at Andreessen Horowitz and cofounder of the firm’s American Dynamism practice, argues this is the biggest business opportunity of our time.

In this conversation from The Shawn Ryan Show, Boyle discusses the rise of defense tech startups, why optimism drives her work, and how a new generation of engineers and founders is rethinking innovation and patriotism in America.

In this interview from the 20VC podcast, Martin Casado (a16z General Partner) joins Harry Stebbings to unpack the state of AI, the rise of coding models, the future of open vs. closed source, and how value is shifting across the stack.

Martin offers a candid view of the opportunities and dangers shaping AI and venture capital today.

What are real consumers actually doing with AI today?

In this episode, a16z consumer investors Olivia Moore and Justine Moore break down the fifth edition of our Consumer AI 100, a biannual ranking of the most used AI-native web and mobile products across the globe.

What exactly is an AI agent, and how will agents change the way we work?

In this episode, a16z general partners Erik Torenberg and Martin Casado sit down with Aaron Levie (CEO, Box) and Steven Sinofsky (a16z board partner; former Microsoft exec) to unpack one of the hottest debates in AI right now.

They cover:
-Competing definitions of an “agent,” from background tasks to autonomous interns
-Why today’s agents look less like a single AGI and more like networks of specialized sub-agents
-The technical challenges of long-running, self-improving systems
-How agent-driven workflows could reshape coding, productivity, and enterprise software
-What history — from the early PC era to the rise of the internet — tells us about platform shifts like this one

The conversation moves from deep technical questions to big-picture implications for founders, enterprises, and the future of work.

Erik Torenberg sits down with Ben Horowitz, Cofounder of a16z, for a candid conversation on venture capital, leadership, and the future of innovation. Recorded live at a16z’s Menlo Park offices in 2023, Ben shares practical wisdom and hard-earned lessons on navigating market cycles, building resilient companies, and why culture is a lasting competitive edge.

Highlights:
Venture Cycles: How today’s market compares to past downturns.
Leadership in Uncertainty: Strategies for guiding teams through volatility.
Founder Resilience: The traits that separate enduring founders.
Culture as Strategy: Why culture determines long-term success.
Investment Lens: How a16z identifies standout startups.
Future Trends: Ben’s predictions on AI, crypto, and beyond.

Marc Andreessen, cofounder Andreessen Horowitz, joins the Hermitix podcast for a conversation on AI, accelerationism, energy, and the future.

From the thermodynamic roots of effective accelerationism (E/acc) to the cultural cycles of optimism and fear around new technologies, Marc shares why AI is best understood as code, how nuclear debates mirror today’s AI concerns, and what these shifts mean for society and progress.

Housing and healthcare make up nearly half of household spending, yet both sectors are riddled with inefficiency and rising costs.

In this episode, Erik Torenberg is joined by a16z Growth partner Alex Immerman and Minna Song and Tony Stoyanov, cofounders of EliseAI, to discuss why they’re tackling these critical industries and how AI can transform everything from leasing and maintenance to patient scheduling and compliance.

The conversation covers:
Why the U.S. is 5 million housing units short — and how technology can help unlock existing supply
How automation can cut waste, reduce labor costs, and improve affordability
What fully autonomous buildings might look like, and how that model could extend to healthcare

This is about the costs that touch every household, and the role AI might play in finally bringing them down.

Do tariffs help rebuild American manufacturing or hold it back?

In this episode, American Compass founder and chief economist Oren Cass sits down with commentator and author Noah Smith and a16z General Partner Erik Torenberg for a lively debate on the future of U.S. industry.

They discuss the case for tariff-driven re-industrialization versus free-market approaches, the role of allies in trade policy, and what the numbers really show about manufacturing jobs, investment, and output. Along the way, they challenge each other’s assumptions and explore what it would take to actually bring more production back to American soil.

The AI hardware race is heating up, and NVIDIA is still far ahead. What will it take to close the gap?

In this episode, Dylan Patel (Founder & CEO, SemiAnalysis) joins Erin Price-Wright (General Partner, a16z), Guido Appenzeller (Partner, a16z), and host Erik Torenberg to break down the state of AI chips, data centers, and infrastructure strategy.

We discuss:
- Why simply copying NVIDIA won’t work, and what it takes to beat them
- How custom silicon from Google, Amazon, and Meta could reshape the market
- The economics of AI model launches and the shift toward cost efficiency
- Infrastructure bottlenecks: power, cooling, and the global supply chain
- The rise of AI silicon startups and the challenges they face
- Export controls, China’s AI ambitions, and geopolitics in the chip race
- Big tech’s next moves: advice for leaders like Jensen Huang, Sundar Pichai, Mark Zuckerberg, and Elon Musk

Genie 3 can generate fully interactive, persistent worlds from just text, in real time.

In this episode, Google DeepMind’s Jack Parker-Holder (Research Scientist) and Shlomi Fruchter (Research Director) join Anjney Midha, Marco Mascorro, and Justine Moore of a16z, with host Erik Torenberg, to discuss how they built it, the breakthrough “special memory” feature, and the future of AI-powered gaming, robotics, and world models.

They share:
-How Genie 3 generates interactive environments in real time
-Why its “special memory” feature is such a breakthrough
-The evolution of generative models and emergent behaviors
-Instruction following, text adherence, and model comparisons
-Potential applications in gaming, robotics, simulation, and more
-What’s next: Genie 4, Genie 5, and the future of world models

This conversation offers a first-hand look at one of the most advanced world models ever created.

a16z General Partners Martin Casado and Anjney Midha join Erik Torenberg to unpack one of the most dramatic shifts in tech policy in recent memory: the move from “pause AI” to “win the AI race.”

They trace the evolution of U.S. AI policy—from executive orders that chilled innovation, to the recent AI Action Plan that puts scientific progress and open source at the center. The discussion covers how technologists were caught off guard, why open source was wrongly equated to nuclear risk, and what changed the narrative—including China's rapid progress.

The conversation also explores:
- How and why the AI discourse got captured by doomerism
- What “marginal risk” really means—and why it matters
- Why open source AI is not just ideology, but business strategy
- How government, academia, and industry are realigning after a fractured few years
- The effect of bad legislation—and what comes next

Whether you're a founder, policymaker, or just trying to make sense of AI's regulatory future, this episode breaks it all down.

We’re sharing an episode from ChinaTalk that dives into one of the biggest recent reversals in U.S. tech policy.

The U.S. banned Nvidia’s H20 AI chips to China in April. Now, just months later, they’re being sold—with a 15% export fee. What happened? Why the reversal? And what does it mean for the future of AI competition between the U.S. and China?

Chris Miller—author of Chip War—and Lennart Heim from RAND join ChinaTalk host Jordan Schneider to unpack the policy flip-flop, why China is publicly downplaying interest in the H20, and why high-bandwidth memory and semiconductor manufacturing tools may be even more important than the Nvidia chips themselves.

Fresh off the announcement of his move from Shopify to a16z, Alex Danco joins TBPN to talk about the “trade deal” that brought him here and his mission to make the firm’s written content truly world class.

He discusses why he believes writing still matters in the age of AI, how great prose can act as “power transfer technology” for founders, and why he’s betting on the overlooked art of speechwriting. Alex also reflects on his years as a founder, investor, and longtime blogger, and shares the formats he’s most excited to explore, from deal memos to launch speeches.

a16z partners Olivia and Justine Moore unpack the latest in consumer AI including:

- Grok’s “Imagine” and its instant, social-first creative tools
- Google’s Genie 3 and the future of 3D worlds
- GPT-5: what’s new, what’s missing, and why some want their old chatbot back
- AI-generated music from ElevenLabs
- Olivia’s vibecoded Jensen Huang selfie app

There’s been a wave of M&A deals lately - Meta and Scale, Windsurf and Google - and a lot of it points to something bigger: how regulation, capital, and innovation are colliding in 2025.

In this episode Erik Torenberg brings together Steven Sinofsky, former Microsoft Executive and Balaji Srinivasan, founder of the Network School, and author of the Network State to break it all down.

From acquihires to “acquifires,” from FTC crackdowns to the deeper battle between the state and the network, this is a sharp conversation on the future of tech and power.

ChatGPT-5 just launched, marking a major milestone for OpenAI and the entire AI ecosystem.

Fresh off the live stream, Erik Torenberg was joined in the studio by three people who played key roles in making this model a reality:

- Christina Kim, Researcher at OpenAI, who leads the core models team on post-training
- Isa Fulford, Researcher at OpenAI, who leads deep research and the ChatGPT agent team on post-training
- Sarah Wang, General Partner at a16z, who’s led our investment in OpenAI since 2021

They discuss what’s actually new in ChatGPT-5—from major leaps in reasoning, coding, and creative writing to meaningful improvements in trustworthiness, behavior, and post-training techniques.

Marc Andreessen joins TBPN for an unfiltered conversation spanning everything from ads in LLMs to why Apple’s AI strategy may be risky for anyone not named Apple.

Marc breaks down the current state of AI: why open source is resurging, how foundational research is (or isn’t) turning into product, and whether we’ve hit the moment when phones start to fade as dominant platforms. He also shares his candid thoughts on Meta’s wearable wins, Vision Pro’s imperfections, and how humor and deep research are his two favorite use cases for AI today.

What happens when a startup becomes a giant—and then has to reinvent itself all over again?

In this episode, Martin Casado sits down with Raghu Raghuram (former CEO of VMware) and Jeetu Patel (President and CPO at Cisco) for a deep, tactical conversation on scaling, disruption, and navigating transformation from the inside. They share hard-won lessons from leading two of the most iconic infrastructure companies in tech—through waves like virtualization, cloud, containers, and now AI.

They cover:
-How to keep innovation alive inside large companies
-Why the best companies operate with a founder’s mindset, even without founders
-The difference between selling to buyers vs. practitioners
-Why the story is the strategy, and how to tell it at scale
-How Cisco is rebuilding its startup DNA in the age of AI

If you're building or leading through a major tech wave, this episode is a playbook.

In this episode, Erik Torenberg is joined in the studio by Dwarkesh Patel and Noah Smith to explore one of the biggest questions in tech: what exactly is artificial general intelligence (AGI), and how close are we to achieving it?

They break down:
-Competing definitions of AGI — economic vs. cognitive vs. “godlike”
-Why reasoning alone isn’t enough — and what capabilities models still lack
-The debate over substitution vs. complementarity between AI and human labor
-What an AI-saturated economy might look like — from growth projections to UBI, sovereign wealth funds, and galaxy-colonizing robots
-How AGI could reshape global power, geopolitics, and the future of work

Along the way, they tackle failed predictions, surprising AI limitations, and the philosophical and economic consequences of building machines that think, and perhaps one day, act, like us.

What really caused the breakdown between tech and media—and what comes next?

Erik Torenberg sits down with Balaji Srinivasan (entrepreneur, investor, and author of The Network State) to explore the long-building conflict between Silicon Valley and legacy journalism. Balaji explains how the collapse of traditional media business models gave rise to political capture, clickbait, and adversarial coverage of the tech industry.

They discuss why “going direct” is no longer optional, how tech became the villain in establishment narratives, and what it would take to build a new truth infrastructure - from decentralized content creation to cryptographic verification.

This episode covers power, distribution, and the future of media, with a signature mix of historical insight, social analysis, and Balaji’s forward-looking frameworks.