Igor Kovalchuk

Epigenetics has a lot to do with an organism’s interaction with the environment; therefore, it is important to review how our understanding of the interactions between the organism’s genome, surroundings, and phenotype has developed over time

There are multiple examples of the influence of environment on the genetic and epigenetic make-up of the organism. The phenomena of stress-induced transposon activation, non-targeted mutagenesis, stress-induced communication between cells and organisms, and evidences of transgenerational changes induced by stress are just some representations of epigenetic effects of the environment on the organism.

the most interesting examples of an epigenetically controlled process. It has already been known that a higher dose of mutagen does not necessarily result in a higher level of damage to DNA. In fact, low doses of ionizing radiation often lead to disproportionally high levels of DNA damage. Doses of ionizing radiation that are believed to have a negligible effect on a cell often exert dramatic influence on DNA damage and cell